abstract：:The obstructive sleep apnea syndrome is common and its prevalence is expected to increase with the current obesity epidemic. If left untreated, it is associated with important morbidity such as growth failure, neurocognitive impairment, systemic and pulmonary hypertension, and endothelial dysfunction. Recent research ...

journal_title：Paediatric respiratory reviews

authors： Tapia IE,Marcus CL

更新日期：2013-09-01 00:00:00

abstract：:Chronic cough has been variably defined as a cough lasting longer than 3, 4 or 8 weeks. Many post viral or pertussis like illnesses are associated with prolonged coughing that resolves over time. Management involves first trying to make a diagnosis and identify the presence of any underlying condition. Targeted treatm...

journal_title：Paediatric respiratory reviews

authors： Shields MD,Doherty GM

更新日期：2013-06-01 00:00:00

abstract：:Allergic diseases are a public health problem in industrialized countries due to the increasing number of allergies related to Western lifestyle. The multiplicity of organs affected by allergy (skin (atopic dermatitis), airway epithelium (respiratory allergy), and digestive tract (food allergy)) worsens the prognosis ...

journal_title：Paediatric respiratory reviews

authors： Just J

更新日期：2013-06-01 00:00:00

abstract：:Cystic fibrosis related diabetes (CFRD) is a common complication of cystic fibrosis, caused by a fall in insulin secretion with age in individuals with pancreatic insufficiency. CFRD is associated with worse clinical status and increased mortality. Treatment of CFRD with insulin results in sustained improvements in lu...

journal_title：Paediatric respiratory reviews

authors： Bridges N

更新日期：2013-05-01 00:00:00

abstract：:This paper describes a patient whose decline over two years was precipitous, from an active independent life with lung function (FEV1) above 50% to requiring transplantation. The main pathogen on sputum culture throughout that period was Scediosporium apiosperum. The epidemiology pathogenicity and treatment of this fu...

journal_title：Paediatric respiratory reviews

authors： Russell GK,Gadhok R,Simmonds NJ

更新日期：2013-05-01 00:00:00

abstract：:The Clinical and Functional Translation of CFTR (CFTR2) project presents a novel approach to clinical and functional annotation of mutations identified in disease-causing genes. Phenotype and genotype information on approximately 40,000 cystic fibrosis (CF) patients were collected from registries and large clinics. Th...

journal_title：Paediatric respiratory reviews

authors： Castellani C,CFTR2 team.

更新日期：2013-05-01 00:00:00

abstract：:Since preschool wheezing is the common expression of several heterogeneous disorders, identification of children at risk for persistent asthma is particularly challenging. To date, efforts to predict the outcome of preschool wheeze have mainly relied on predictive rules consisting of simple clinical and laboratory par...

journal_title：Paediatric respiratory reviews

authors： Fouzas S,Brand PL

更新日期：2013-03-01 00:00:00

abstract：:Bacterial 'colonisation' of the nasopharynx by potential bacterial pathogens is frequent in early childhood and is frequent as part of a dynamic process in which the microbiota of the oral and nasopharynx are established. New understanding recognizes this process is evolving and that competition and likely regulation ...

journal_title：Paediatric respiratory reviews

authors： Pelton SI

更新日期：2012-09-01 00:00:00

abstract：:This paper is an attempt to convey in a lucid way how to go about writing a scientific article for publication in an appropriate journal. Topics covered are: a) reasons to write a paper b) types of papers c) asking a question and formulating an hypothesis d) the complex series of steps necessary before you begin your ...

journal_title：Paediatric respiratory reviews

authors： Chernick V

更新日期：2012-06-01 00:00:00

abstract：:There are many important respiratory manifestations of endocrine and metabolic diseases in children. Acute and chronic pulmonary infections are the most common respiratory abnormalities in patients with diabetes mellitus, although cardiogenic and non-cardiogenic pulmonary oedema are also possible. Pseudohypoaldosteron...

journal_title：Paediatric respiratory reviews

authors： Milla CE,Zirbes J

更新日期：2012-03-01 00:00:00

abstract：:Asthma is a heterogeneous disease and it is therefore unrealistic to expect that inhaled corticosteroids (ICS) would be appropriate first line preventer therapy for all children with asthma. There is good theoretical and clinical trial evidence demonstrating that leukotriene receptor antagonists (LTRAs) are more effec...

journal_title：Paediatric respiratory reviews

authors： van Asperen PP

更新日期：2011-12-01 00:00:00

abstract：:There are multiple aetiologies for childhood bronchiectasis unrelated to cystic fibrosis. Some of these aetiologies, such as those predisposing to recurrent lung infections, e.g. immunodeficiencies, require treatment of the underlying condition and disease-specific pulmonary pathogens within the airway. Regardless of ...

journal_title：Paediatric respiratory reviews

authors： Redding GJ

更新日期：2011-06-01 00:00:00

abstract：:Childhood pulmonary TB (PTB) is under diagnosed, in part due to difficulties in obtaining microbiological confirmation. However, given the poor specificity of clinical diagnosis, microbiological confirmation and drug susceptibility testing is important in guiding appropriate therapy especially in the context of drug r...

journal_title：Paediatric respiratory reviews

authors： Nicol MP,Zar HJ

更新日期：2011-03-01 00:00:00

abstract：:Dysfunctional breathing, hyperventilation and vocal cord dysfunction are frequently seen in children and adults. The prevalence is unknown. There are no standardized diagnostic criteria, and for now, effective exclusion of organic disease leaves the diagnosis of dysfunctional breathing. Therapy is mainly focussed on e...

journal_title：Paediatric respiratory reviews

authors： de Groot EP

更新日期：2011-03-01 00:00:00

abstract：:Sudden unexpected death is one of the most frequent ways of dying in the first year of life after the neonatal period. It is however, much less frequent after the first birthday. Investigations into the cause of death are very important, for a significant proportion of these sudden deaths can be explained only after a...

journal_title：Paediatric respiratory reviews

authors： Côté A

更新日期：2010-12-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth. Chest imaging is important in making the diagnosis of BPD, and in assessing for complications. More recently computerised tomography (CT) scanning has provided insights in to the pathophysiology of BPD. Studies in infants, young and school age...

journal_title：Paediatric respiratory reviews

authors： Wilson AC

更新日期：2010-09-01 00:00:00

abstract：:Cardiac abnormalities occur in association with many of the neuromuscular disorders that present in childhood. Genetic defects involving the cytoskeleton, nuclear membrane, and mitochondrial function have all been described in patients with skeletal myopathy and cardiac involvement. The most common classes of neuromus...

journal_title：Paediatric respiratory reviews

authors： Hsu DT

更新日期：2010-03-01 00:00:00

abstract：:Chylothorax is the accumulation of chyle in the pleural space, as a result of damage to the thoracic duct. Chyle is milky fluid enriched with fat secreted from the intestinal cells and lymphatic fluid. Chylothorax in children, is most commonly seen as a complication of cardiothoracic surgery but may occur in newborns ...

journal_title：Paediatric respiratory reviews

authors： Soto-Martinez M,Massie J

更新日期：2009-12-01 00:00:00

abstract：:Regular exercise and habitual physical activity are important for patients with cystic fibrosis (CF). Research has demonstrated the benefits of aerobic, anaerobic, and strength exercise training programs for health and quality of life, however, the CF patient is faced with unique barriers and challenges to participati...

journal_title：Paediatric respiratory reviews

authors： Wilkes DL,Schneiderman JE,Nguyen T,Heale L,Moola F,Ratjen F,Coates AL,Wells GD

更新日期：2009-09-01 00:00:00

abstract：:Primary ciliary dyskinesia (PCD) is a rare, autosomal recessive condition. The signs and symptoms are due to congenital abnormalities of ciliary structure and function, resulting in impaired mucociliary clearance. This affects the ciliated epithelium lining the nose, sinuses, Eustachian tube and airways. As a conseque...

journal_title：Paediatric respiratory reviews

authors： Hogg C

更新日期：2009-06-01 00:00:00

abstract：:Our aim was to obtain knowledge of how meteorological conditions affect community epidemics of respiratory syncytial virus (RSV) infection. We recorded year-round RSV activity in nine cities that differ markedly in geographic location and climate. We correlated local weather conditions with weekly or monthly RSV cases...

journal_title：Paediatric respiratory reviews

authors： Welliver R

更新日期：2009-06-01 00:00:00

abstract：:The major morbidity and mortality associated with cerebral palsy (CP) relates to respiratory compromise. This manifests through repeated pulmonary aspiration, airway colonization with pathogenic bacteria, the evolution of bronchiectasis and sleep disordered breathing. An accurate assessment involving a multidisciplina...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA,Follett J,Van Asperen PP

更新日期：2009-03-01 00:00:00

abstract：:Comprehensive newborn screening for cystic fibrosis has occurred for more than 25 years in some regions and the results of randomised controlled trials reporting the outcomes have been published. Testing protocols for CF have recently been reviewed and the sensitivity and specificity of these protocols are high. In sp...

journal_title：Paediatric respiratory reviews

authors： McKay K,Wilcken B

更新日期：2008-12-01 00:00:00

abstract：:During sleep changes in central and peripheral neurological pathways and muscle tone result in unique vulnerabilities in the respiratory system. Abnormalities of the respiratory system that are not apparent in wakefulness can become evident during particular sleep states, making overnight polysomnography (PSG) a valua...

journal_title：Paediatric respiratory reviews

authors： Waters K

更新日期：2008-09-01 00:00:00

abstract：:Since experienced clinicians spend a substantial proportion of their time teaching and supervising trainees, a working knowledge of adult learning is of value. This knowledge will not only make you a more effective teacher, but will be of benefit to you when you are learning new information. There are a number of impo...

journal_title：Paediatric respiratory reviews

authors： Mellis CM

更新日期：2008-06-01 00:00:00

abstract：:Spinal muscular atrophy (SMA) is a relatively common, profoundly disabling and incurable disease that presents in early childhood with hypotonia, weakness and decreased movement. Without ventilatory support, premature death from respiratory insufficiency is universal in children with spinal muscular atrophy type 1 (SM...

journal_title：Paediatric respiratory reviews

authors： Ryan MM

更新日期：2008-03-01 00:00:00

abstract：:The dynamic interaction between the heart and lungs leads to a degree of respiratory co-morbidity including both restrictive and obstructive airway abnormalities, which may be overlooked in children with congenital and acquired heart disease. The improving imaging techniques of the heart, both foetal and post-natal co...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA,Sherwood M

更新日期：2007-12-01 00:00:00

abstract：:This article will review traditional and newer microbiological techniques for the diagnosis of mycobacterial respiratory infections. It will concentrate on the diagnosis of infections due to Mycobacterium tuberculosis, the main mycobacterium causing respiratory infections of clinical and public health importance. The ...

journal_title：Paediatric respiratory reviews

authors： Andresen D

更新日期：2007-09-01 00:00:00

abstract：:Vocal cord dysfunction is characterised by paradoxical vocal cord adduction that occurs during inspiration, resulting in symptoms of dyspnoea, wheeze, chest or throat tightness and cough. Although the condition is well described in children and adults, confusion with asthma often triggers the use of an aggressive trea...

journal_title：Paediatric respiratory reviews

authors： Noyes BE,Kemp JS

更新日期：2007-06-01 00:00:00

abstract：:With the advent of improved antenatal imaging over the past 10 years, the diagnosis, assessment and management of congenital cystic lung abnormalities have changed. These were once considered the exclusive domain of the surgeon, who had the authority to operate on all congenital cystic lung abnormalities regardless of...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA

更新日期：2007-03-01 00:00:00

abstract：:Obese adolescents, particularly those with extreme obesity (body mass index > or =40 kg/m(2)), are developing serious medical complications at an unexpectedly high rate. As non-operative approaches to weight loss have shown less than optimal results, paediatric patients are increasingly seeking bariatric surgical inte...

journal_title：Paediatric respiratory reviews

authors： Kalra M,Inge T

更新日期：2006-12-01 00:00:00

abstract：:There are hardly any controlled studies in paediatric tracheostomy care; instead, most established standards, procedures and details have been elaborated at the bedside by trial and error. Once the appropriate tube is chosen, tube care consists of tube change, fixation, management of secretions, humidification of insp...

journal_title：Paediatric respiratory reviews

authors： Oberwaldner B,Eber E

更新日期：2006-09-01 00:00:00

abstract：:One of the most active areas of research in medicine today is stem cell biology. This review introduces the reader to the field of stem cell biology and its therapeutic potential. More importantly, the potential application of stem cell therapy in acute lung injury will be explored. ...

journal_title：Paediatric respiratory reviews

authors： Sanders RC Jr,Slayton WB,Cogle CR,Fisher RC,Scott EW

更新日期：2006-06-01 00:00:00

abstract：:Cough is a common presenting symptom to paediatricians and paediatric respiratory physicians. The causes of chronic cough in childhood are significantly different from those in adults, and a different approach to diagnosis and management is needed. In most cases cause can be identified or a satisfactory label given. T...

journal_title：Paediatric respiratory reviews

authors： Massie J

更新日期：2006-03-01 00:00:00

abstract：:Allergic bronchopulmonary aspergillosis (ABPA) is a severe complication in children, adolescents and adults with cystic fibrosis (CF), the prevalence of which ranges from 6-25%. The disease is the result of the colonisation of the respiratory tract by fungi of the genus Aspergillus, commonly Aspergillus fumigatus, and...

journal_title：Paediatric respiratory reviews

authors： de Almeida MB,Bussamra MH,Rodrigues JC

更新日期：2006-03-01 00:00:00

abstract：:Pneumonia is highly prevalent in both developed and developing countries. In this review we list the main organisms affecting children with pneumonia and we propose a summary of the best possible diagnostic and therapeutic measures. ...

journal_title：Paediatric respiratory reviews

authors： Stein RT,Marostica PJ

更新日期：2006-01-01 00:00:00

abstract：:Since the discovery of the CF gene over a decade ago, several groups worldwide have explored the potential of gene therapy, the insertion of a normal copy of the gene into the respiratory epithelium. Both viral and synthetic gene transfer agents have been designed to this end, although problems with repeat application...

journal_title：Paediatric respiratory reviews

authors： Davies JC

更新日期：2006-01-01 00:00:00

abstract：:The term "mucoactive agent" refers to any medication used to improve the clearance of airway secretions. It is not synonymous with the word "mucolytic" as this strictly means a drug that decreases the viscosity of secretions. In many cases, decreased viscosity will adversely affect cough transport. For this reason man...

journal_title：Paediatric respiratory reviews

authors： Rubin BK

更新日期：2006-01-01 00:00:00

abstract：:Asthma is most frequent chronic disease in childhood. Childhood asthma frequently persists to adulthood and the available evidence suggests that the severity of childhood asthma predicts the severity of asthma in the adulthood. To prevent long term remodeling of the airways and improve prognosis, early diagnosis and t...

journal_title：Paediatric respiratory reviews

authors： Pohunek P

更新日期：2006-01-01 00:00:00

abstract：:The interrupter technique (Rint) is a quick, easy and effort-independent way to obtain indirect measurements of airways resistance in the preschool child. Results may be obtained using a portable Rint machine or a whole-body plethysmograph. Normative data are available and recent studies have improved standardisation ...

journal_title：Paediatric respiratory reviews

authors： Child F

更新日期：2005-12-01 00:00:00